One of the authors of the study (Heden) was quoted as saying "The mass media and many health care practitioners often advocate eating several small meals throughout the day. However, when we examined the literature, we didn't find many studies examining or supporting this popular claim. This lack of research led to our study, which is one of the first to examine how meal frequency affects insulin and blood-fat levels in obese women during an entire day of eating."
Our body needs to secrete bile from the liver/gallbladder, acid from the stomach, and digestive enzymes from the pancreas in order to properly digest food. Building up an "appetite" includes preparing all these digestive components. If your digestive tract is being constantly bombarded by small quantities of food; how can it know when to secrete, when to digest, and when to relax the sphincter at the bottom of the stomach and release the partially digested food into the intestines?